Publications – Montagne Lab

Complete list here 👉🏻 https://bit.ly/2Uu64Xs

Pericyte loss and endothelial activation define distinct vascular states in cerebral small vessel disease. Acta Neuropathol. 2026; 152, 53. https://doi.org/10.1007/s00401-026-03102-6. Chagnot A, Jaime Garcia D, McQuaid C, Cholewa-Waclaw J, McDade K, Dando O, Wardlaw JM, Smith C, Montagne A.
Pericyte Loss Reprogrammes Capillary Endothelium and Drives White Matter Injury in Small Vessel Disease. bioRxiv, 2026 May 11; 724300. doi: https://doi.org/10.64898/2026.05.11.724300. D. Stefancova, A. Chagnot, M. Sewell, N. Fialova, C. McQuaid, O.J. Uweru, S. Becker, M. Romero-Bernal, W. Mungall, V. Walczak-Gillies, T.D. Farr, R. Lennen, M.A. Jansen, O. Dando, J. Cholewa-Waclaw, Montagne A.
Cerebral Intramural Cells: A Missing Cellular Link Between Vascular Aging and Alzheimer’s Disease. Int J Mol Sci. 2026 Aug 17;27(16):7353. doi: 10.3390/ijms27167353. Arbănași EM, Arbănași EM, Boghițoiu TG, Cărare SA, Cordoș BA, Braysh K, Suciu N, Chinezu L, Manu DR, Montagne A, Dewing J, Russu E, Bănescu CV, Voidăzan ST, Cărare RO. PMID: 42653355.
Friend or foe? Glial-vascular interactions in health and neurodegenerative disease. Pharmacol Rev. 2026 Jul;78(4):100143. doi: 10.1016/j.pharmr.2026.100143. McQuaid C, Sewell M, Montagne A. PMID: 42229063.
Abrupt Pericyte Loss Precedes Endothelial Activation in Cerebral Small Vessel Disease. bioRxiv, 2026 Mar 19; 713028. doi: https://doi.org/10.64898/2026.03.19.713028. Chagnot A, Jaime Garcia D, McQuaid C, Cholewa-Waclaw J, McDade K, Dando O, Wardlaw JM, Smith C, Montagne A.
Placental prostaglandin signalling disrupts barrier integrity and relays an acute inflammatory signal to the fetus. bioRxiv, 2026 Mar 11; 706681. doi: https://doi.org/10.64898/2026.03.11.706681. Horackova H, Zhao Q, Faulkner S, Alvarez J, Akiz C, Liu Y, Crosthwait J, Dai W, Santoyo D, Pham-Chang D, Bhinderwala N, Tagliaferro T, Wallace WD, Walia S, Martinovic J, Baldauf C, Montagne A, Bonnin A.
APOE4 genotype is associated with reduced cortical VEGFR2 (KDR) transcript levels independent of endothelial abundance: and AMP-AD RNA-seq pilot study. bioRxiv, 2026 Mar 01; 708815. doi: https://doi.org/10.64898/2026.03.01.708815. Laing KK, Montagne A.
Impact of Apolipoprotein E4 on blood-brain barrier integrity in target replacement murine models: a systematic review and meta-analysis. Alzheimers Res Ther. 2026 May 7;18(1):119. doi: 10.1186/s13195-026-02018-3. Laing KK, Fialova N, Wardlaw J, Montagne A. IPMID: 42098772.
Performance evaluation of the nanoScan® P123S total-body PET. EJNMMI Phys. 2025 Dec 8. doi: 10.1186/s40658-025-00817-5. Réti D, Corral CA, Cranston I, Reid VJM, O’Rourke KM, Morgan TEF, Montagne A, Jansen MA, Burianova VK, Sutherland A, Major P, Nagy K, Bagaméry G, Tavares AAS. PMID: 41359287.
The blood-brain barrier. Curr Biol. 2025; 35(20):R1010-15. Chagnot A, Montagne A. PMID: 41118727.
Walking on the tightrope: the shared roles of the bridging pericytes in the brain. Front Cell Neurosci. 2025; 19:1615579. doi: 10.3389/fncel.2025.1615579. eCollection 2025. Chagnot A, Montagne A. PMID: 40766182.
Blood biomarkers of vascular dysfunction in small vessel disease progression: Insights from a longitudinal neuroimaging study. Alzheimers Dement. 2025; 21:e70152. https://doi.org/10.1002/alz.70152. Jaime Garcia D, Clancy U, Arteaga C, Valdés-Hernandez MC, Chappell FM, Jochems ACC, Cheng Y, Zhang J, Thrippleton MJ, Stringer MS, Sleight E, Backhouse EV, Wiseman S, Brown R, Doubal FN, Montagne A, Wardlaw JM, The MSS3 Study Group. PMID: 40275856.
Unraveling the transcriptomic landscape of brain vascular cells in dementia: A systematic review. Alzheimers Dement. 2025 Jan 14. doi: 10.1002/alz.14512. Sewell M, Fialova N, Montagne A. PMID: 39807599.
Atp13a5 Marker Reveals Pericyte Specification in the Mouse Central Nervous System. J Neurosci. 2024 Oct 23; 44(43):e0727242024. doi: 10.1523/JNEUROSCI.0727-24.2024. Guo X, Xia S, Ge T, Lin Y, Hu S, Wu H, Xie X, Zhang B, Zhang S, Zeng J, Chen JF, Montagne A, Gao F, Ma Q, Zhao Z. PMID: 39261008.
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice. Nat Neurosci. 2024 Sep; 27(9):1721-1733; doi: 10.1038/s41593-024-01695-3. Levard D, Seillier C, Bellemain-Sagnard M, Fournier AP, Lemarchand E, Dembech C, Riou G, McDade K, Smith C, McQuaid C, Montagne A, Amann L, Prinz M, Vivien D, Rubio M. PMID: 38961228.
Microglia protect against age-associated brain pathologies. Neuron. 2024; 112(16):2732-2748.e8; doi: 10.1016/j.neuron.2024.05.018. Munro DAD, Bestard-Cuche N, McQuaid C, Chagnot A, Shabestari SK, Chadarevian JP, Maheshwari U, Szymkowiak S, Morris K, Mohammad M, Corsinotti A, Bradford B, Mabbott N, Lennen RJ, Jansen MA, Pridans C, McColl BW, Keller A, Blurton-Jones M, Montagne A, Williams A, Priller J. PMID: 38897208.
Heterogeneous blood-brain barrier disruption in cerebral small vessel disease. Alzheimers Dement. 2024 Jul; 20(7):4527-4539; doi: 10.1002/alz.13874. Ying Y, Li Y, Yao T, Shao X, Tang W, Montagne A, Chabriat H, Wang DJJ, Wang C, Yang Q, Cheng X. PMID: 38787758.
A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer’s disease. Nat Commun. 2024 Mar 12; 15(1):2243; doi: 10.1038/s41467-024-46630-z. Tsartsalis S, Sleven H, Fancy N, Wessely F, Smith AM, Willumsen N, Cheung TKD, Rokicki MJ, Chau V, Ifie E, Khozoie C, Ansorge O, Yang X, Jenkyns MH, Davey K, McGarry A, Muirhead RCJ, Debette S, Jackson JS, Montagne A, Owen DR, Miners JS, Love S, Webber C, Cader MZ, Matthews PM. PMID: 38472200.
Connexins and blood-brain barrier: Beyond the gap. Neuron. 2023; 111(22)3499-3501. https://doi.org/10.1016/j.neuron.2023.10.032. Chagnot A, Montagne A. PMID: 37972562.
A Scoping Review on Biomarkers of Endothelial Dysfunction in Small Vessel Disease: Molecular Insights from Human Studies. Int J Mol Sci. 2023; 24(17):13114. Jaime Garcia D, Chagnot A, Wardlaw JM, Montagne A. PMID: 37685924.
Editorial: Imaging of the blood-brain barrier in Alzheimer’s disease and related disorders. Front Aging Neurosci. 2023 Jul 14; 15:1252581. doi: 10.3389/fnagi.2023.1252581. Uchida Y, Shao X, Montagne A, Matsukawa N. PMID: 35755776.
SARS-CoV-2 and vascular dysfunction: a growing role for pericytes. Cardiovasc Res.2022 Sep 5:cvac143; doi: 10.1093/cvr/cvac143. McQuaid C, Montagne A. PMID: 36063106.
Editorial: Multifaceted interactions between immunity and the diseased brain. Front Cell Neurosci. 2022 Jun 8; 16:941590; doi: 10.3389/fncel.2022.941590. Funk KE, Montagne A, Falcao AM, Da Mesquita S. PMID: 35755776.
Imaging subtle leaks in the blood-brain barrier in the aging human brain: potential pitfalls, challenges and possible solutions. GeroScience. 2022 Apr 25; doi: 10.1007/s11357-022-00571-x. Montagne A, Barnes SR, Nation DA, Kisler K, Toga AW, Zlokovic BV. PMID: 35469116.
Prenatal disruption of blood-brain barrier formation via cyclooxygenase activation leads to life-long brain inflammation. PNAS. 2022 Apr 12; 119(15):e2113310119. Zhao Q, Dai W, Chen HY, Jacobs RE, Zlokovic BV, Lund BT, Montagne A, Bonnin A. PMID: 35377817.
Blood-brain barrier link to human cognitive impairment and Alzheimer’s Disease. Nat Cardiovasc Res. 2022 Feb; 1(2):108-115. Barisano G, Montagne A, Kisler K, Schneider JA, Wardlaw JM, Zlokovic BV. PMID: 35450117.
Air pollution particulate matter amplifies white matter vascular pathology and demyelination caused by hypoperfusion. Front Immunol. 2021 Nov 16; 12:785519. Huuskonen MT, Liu Q, Lamorie-Foote K, Shkirkova K, Connor M, Patel A, Montagne A, Baertsch H, Sioutas C, Morgan TE, Finch CE, Zlokovic BV, Mack WJ. PMID: 34868068.
Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C. J Exp Med. 2022 Jan 3; 219(1):e20211372. Huuskonen MT, Wang Y, Nikolakopoulou AM, Montagne A, Dai Z, Lazic D, Sagare AP, Zhao Z, Fernandez JA, Griffin JH, Zlokovic BV. PMID: 34846535.
Air Pollution Particulate Matter Exposure and Chronic Cerebral Hypoperfusion and Measures of White Matter Injury in a Murine Model. Environ Health Perspect. 2021 Aug; 129(8):87006. Liu Q, Shkirkova K, Lamorie-Foote K, Connor M, Patel A, Babadjouni R, Huuskonen M, Montagne A, Baertsch H, Zhang H, Chen JC, Mack WJ, Walcott BP, Zlokovic BV, Sioutas C, Morgan TE, Finch CE, Mack WJ. PMID: 34424052.
Magnetic Resonance Imaging of Blood-Brain Barrier Permeability in Dementia. Neuroscience. 2021 Oct 15; 474:14-29. Chagnot A, Barnes SR, Montagne A. PMID: 34400249.
Interplay between brain pericytes and endothelial cells in dementia. Am J Pathol. 2021 Nov; 191(11):1917-1931. Procter T, Williams A, Montagne A. PMID: 34329605.
APOE4 accelerates advanced stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β. Nature Aging. 2021; 1:506–520. Montagne A, Nikolakopoulou AM, Huuskonen MT, Sagare AP, Lawson EJ, Lazic D, Rege SV, Grond A, Zuniga E, Barnes SR, Prince J, Sagare M, Hsu CJ, LaDu MJ, Jacobs RE, Zlokovic BV. PMID: 35291561.
Alzheimer’s Pathogenic Mechanisms and underlying Sex Difference. Cell Mol Life Sci. 2021 Jun; 78(11):4907-4920. Zhu D, Montagne A, Zhao Z. PMID: 33844047.
Evidence that blood-CSF barrier transport, but not inflammatory biomarkers, change in migraine, while CSF sVCAM1 associates with migraine frequency and CSF fibrinogen. Headache. 2021 Mar; 61(3):536-545. Cowan RP, Gross NB, Sweeney MD, Sagare AP, Montagne A, Arakaki X, Fonteh AN, Zlokovic BV, Pogoda JM, Harrington MG. PMID: 33724462.
Endothelial LRP1 maintains the blood-brain barrier and neuronal function via cyclophilin A. J Exp Med. 2021 Apr 5; 218(4):e20202207. Nikolakopoulou AM, Wang Y, Ma Q, Sagare AP, Montagne A, Huuskonen MT, Rege SV, Dai Z, Kisler K, Körbelin J, Herz J, Zhao Z, Zlokovic BV. PMID: 33533918.
New mechanistic insights, novel treatment paradigms, and clinical progress in cerebrovascular diseases. Front Aging Neurosci. 2021 Jan 28; 13:623751. Boltze J, Aronoswski JA, Badaut J, Buckwalter MS, Caleo M, Chopp M, Dave KR, Didwischus N, Dijkhuizen RM, Doeppner TR, Dreier JP, Fouad K, Gelderblom M, Gertz K, Gołubczyk D, Gregson B, Hamel E, Hanley D, Härtig W, Hummel FC, Ikhsan M, Janowski M, Jolkkonen J, Karuppagounder SS, Keep RF, Koerte IK, Kokaia Z, Li P, Liu F, Lizasoain I, Ludewig P, Metz G, Montagne A, Obenaus A, Palumbo A, Pearl M, Perez-Pinzon M, Planas AM, Plesnila N, Popa-Wagner A, Raval AP, Rueger MA, Sansing LH, Sohrabji F, Stagg CJ, Stetler RA, Stowe A, Sun D, Taguchi A, Tanter M, Vay SU, Vemuganti R, Vivien D, Walczak P, Wang J, Xiong Y, Zille M. PMID: 33584250
Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis.Cell. 2021 Jan 7; 184(1):243-256.e18. Yu M, Ma L, Yuan Y, Ye X, Montagne A, He J, Ho TV, Wu Y, Zhao Z, Sta Maria N, Jacobs R, Urata M, Wang H, Zlokovic BV, Chen JF, Chai Y. PMID: 33417861.
A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease.Transl Stroke Res. 2021 Feb; 12(1):15-30. Stringer MS, Lee H, Huuskonen MT, MacIntosh BJ, Brown R, Montagne A, Atwi S, Ramirez J, Jansen MA, Marshall I, Black SE, Zlokovic BV, Benveniste H, Wardlaw JM. PMID: 32936435.
Comparison Between Blood-Brain Barrier Water Exchange Rate and Permeability to Gadolinium-Based Contrast Agent in an Elderly Cohort. Front Neurosci. 2020 Nov 30; 14:571480. Shao X, Jann K, Ma SJ, Yan L, Montagne A, Ringman JM, Zlokovic BV, Wang DJJ. PMID: 33328848.
APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline. Nature. 2020 05; 581(7806):71-76. Montagne A, Nation DA, Sagare AP, Barisano G, Sweeney MD, Chakhoyan A, Pachicano M, Joe E, Nelson AR, D’Orazio LM, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Reiman EM, Caselli RJ, Chui HC, Tcw J, Chen Y, Pa J, Conti PS, Law M, Toga AW, Zlokovic BV. PMID: 32376954.
A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease. Transl Stroke Res. 2021 Feb; 12(1):15-30. Stringer MS, Lee H, Huuskonen MT, MacIntosh BJ, Brown R, Montagne A, Atwi S, Ramirez J, Jansen MA, Marshall I, Black SE, Zlokovic BV, Benveniste H, Wardlaw JM. PMID: 32936435.
A novel sensitive assay for detection of a biomarker of pericyte injury in cerebrospinal fluid. Alzheimers Dement. 2020 Jun; 16(6):821-830. Sweeney MD, Sagare AP, Pachicano M, Harrington MG, Joe E, Chui HC, Schneider LS, Montagne A, Ringman JM, Fagan AM, Morris JC, Pa J, Nation DA, Toga AW, Zlokovic BV. PMID: 32301266.
Perivascular spaces in the brain: anatomy, physiology and pathology. Nat Rev Neurol. 2020 03; 16(3):137-153. Wardlaw JM, Benveniste H, Nedergaard M, Zlokovic BV, Mestre H, Lee H, Doubal FN, Brown R, Ramirez J, MacIntosh BJ, Tannenbaum A, Ballerini L, Rungta RL, Boido D, Sweeney M, Montagne A, Charpak S, Joutel A, Smith KJ, Black SE. PMID: 32094487.
APOE4 Accelerates Development of Dementia After Stroke: Is There a Role for Cerebrovascular Dysfunction? Stroke. 2020 03; 51(3):699-700. Montagne A, Nation DA, Zlokovic BV. PMID: 32070225.
Proceedings from the Albert Charitable Trust Inaugural Workshop on white matter and cognition in aging. Geroscience. 2020 02; 42(1):81-96. Sorond FA, Whitehead S, Arai K, Arnold D, Carmichael ST, De Carli C, Duering M, Fornage M, Flores-Obando RE, Graff-Radford J, Hamel E, Hess DC, Ihara M, Jensen MK, Markus HS, Montagne A, Rosenberg G, Shih AY, Smith EE, Thiel A, Tse KH, Wilcock D, Barone F. PMID: 31811528.
Undetectable gadolinium brain retention in individuals with an age-dependent blood-brain barrier breakdown in the hippocampus and mild cognitive impairment. Alzheimers Dement. 2019 12; 15(12):1568-1575. Montagne A, Huuskonen MT, Rajagopal G, Sweeney MD, Nation DA, Sepehrband F, D’Orazio LM, Harrington MG, Chui HC, Law M, Toga AW, Zlokovic BV. PMID: 31862169.
Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss. Nat Neurosci. 2019 07; 22(7):1089-1098. Nikolakopoulou AM, Montagne A, Kisler K, Dai Z, Wang Y, Huuskonen MT, Sagare AP, Lazic D, Sweeney MD, Kong P, Wang M, Owens NC, Lawson EJ, Xie X, Zhao Z, Zlokovic BV. PMID: 31235908.
Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction. Nat Med. 2019 02; 25(2):270-276. Nation DA, Sweeney MD, Montagne A, Sagare AP, D’Orazio LM, Pachicano M, Sepehrband F, Nelson AR, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Chui HC, Law M, Toga AW, Zlokovic BV. PMID: 30643288.
Blood-Brain Barrier: From Physiology to Disease and Back. Physiol Rev. 2019 01 01; 99(1):21-78. Sweeney MD, Zhao Z, Montagne A, Nelson AR, Zlokovic BV. PMID: 30280653.
Vascular dysfunction-The disregarded partner of Alzheimer’s disease. Alzheimers Dement. 2019 01; 15(1):158-167. Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, Benveniste H, Dichgans M, Iadecola C, Love S, Bath PM, Markus HS, Salman RA, Allan SM, Quinn TJ, Kalaria RN, Werring DJ, Carare RO, Touyz RM, Williams SCR, Moskowitz MA, Katusic ZS, Lutz SE, Lazarov O, Minshall RD, Rehman J, Davis TP, Wellington CL, González HM, Yuan C, Lockhart SN, Hughes TM, Chen CLH, Sachdev P, O’Brien JT, Skoog I, Pantoni L, Gustafson DR, Biessels GJ, Wallin A, Smith EE, Mok V, Wong A, Passmore P, Barkof F, Muller M, Breteler MMB, Román GC, Hamel E, Seshadri S, Gottesman RF, van Buchem MA, Arvanitakis Z, Schneider JA, Drewes LR, Hachinski V, Finch CE, Toga AW, Wardlaw JM, Zlokovic BV. PMID: 30642436.
The role of brain vasculature in neurodegenerative disorders. Nat Neurosci. 2018 10; 21(10):1318-1331. Sweeney MD, Kisler K, Montagne A, Toga AW, Zlokovic BV. PMID: 30250261.
Permeability imaging as a predictor of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2018 06; 38(6):973-979. Russin JJ, Montagne A, D’Amore F, He S, Shiroishi MS, Rennert RC, Depetris J, Zlokovic BV, Mack WJ. PMID: 29611451.
Pericyte degeneration causes white matter dysfunction in the mouse central nervous system. Nat Med. 2018 03; 24(3):326-337. Montagne A, Nikolakopoulou AM, Zhao Z, Sagare AP, Si G, Lazic D, Barnes SR, Daianu M, Ramanathan A, Go A, Lawson EJ, Wang Y, Mack WJ, Thompson PM, Schneider JA, Varkey J, Langen R, Mullins E, Jacobs RE, Zlokovic BV. PMID: 29400711. (RETRACTED)
Alzheimer’s disease: A matter of blood-brain barrier dysfunction? J Exp Med. 2017 Nov 06; 214(11):3151-3169. Montagne A, Zhao Z, Zlokovic BV. PMID: 29061693.
Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease. Nat Rev Neurosci. 2017 07; 18(7):419-434. Kisler K, Nelson AR, Montagne A, Zlokovic BV. PMID: 28515434.
Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-ß signaling. PLoS One. 2017; 12(4):e0176225. Nikolakopoulou AM, Zhao Z, Montagne A, Zlokovic BV. PMID: 28441414.
Brain imaging of neurovascular dysfunction in Alzheimer’s disease. Acta Neuropathol. 2016 May; 131(5):687-707. Montagne A, Nation DA, Pa J, Sweeney MD, Toga AW, Zlokovic BV. PMID: 27038189.
Blood-Brain Barrier Permeability and Gadolinium: Benefits and Potential Pitfalls in Research. JAMA Neurol. 2016 Jan; 73(1):13-4. Montagne A, Toga AW, Zlokovic BV. PMID: 26524294.
Tissue Plasminogen Activator Expression Is Restricted to Subsets of Excitatory Pyramidal Glutamatergic Neurons. Mol Neurobiol. 2016 09; 53(7):5000-12. Louessard M, Lacroix A, Martineau M, Mondielli G, Montagne A, Lesept F, Lambolez B, Cauli B, Mothet JP, Vivien D, Maubert E. PMID: 26377106.
ROCKETSHIP: a flexible and modular software tool for the planning, processing and analysis of dynamic MRI studies. BMC Med Imaging. 2015 Jun 16; 15:19. Barnes SR, Ng TS, Santa-Maria N, Montagne A, Zlokovic BV, Jacobs RE. PMID: 26076957.
Optimal acquisition and modeling parameters for accurate assessment of low Ktrans blood-brain barrier permeability using dynamic contrast-enhanced MRI. Magn Reson Med. 2016 May; 75(5):1967-77. Barnes SR, Ng TS, Montagne A, Law M, Zlokovic BV, Jacobs RE. PMID: 26077645.
Vascular plasticity and cognition during normal aging and dementia. JAMA Neurol. 2015 May; 72(5):495-6. Montagne A, Pa J, Zlokovic BV. PMID: 25751405.
Impact of alcohol consumption on the outcome of ischemic stroke and thrombolysis: role of the hepatic clearance of tissue-type plasminogen activator. Stroke. 2015 Jun; 46(6):1641-50. Lemarchand E, Gauberti M, Martinez de Lizarrondo S, Villain H, Repessé Y, Montagne A, Vivien D, Ali C, Rubio M. PMID: 25922513.
7T Multi-shell Hybrid Diffusion Imaging (HYDI) for Mapping Brain Connectivity in Mice. Proc SPIE Int Soc Opt Eng. 2015 Mar 20; 9413. Daianu M, Jahanshad N, Villalon-Reina JE, Prasad G, Jacobs RE, Barnes S, Zlokovic BV, Montagne A, Thompson PM. PMID: 25859293.
Blood-brain barrier breakdown in the aging human hippocampus. Neuron. 2015 Jan 21; 85(2):296-302. Montagne A, Barnes SR, Sweeney MD, Halliday MR, Sagare AP, Zhao Z, Toga AW, Jacobs RE, Liu CY, Amezcua L, Harrington MG, Chui HC, Law M, Zlokovic BV. PMID: 25611508.
Molecular magnetic resonance imaging of brain-immune interactions. Front Cell Neurosci. 2014; 8:389. Gauberti M, Montagne A, Quenault A, Vivien D. PMID: 25505871.
Urokinase versus Alteplase for intraventricular hemorrhage fibrinolysis. Neuropharmacology. 2014 Oct; 85:158-65. Gaberel T, Montagne A, Lesept F, Gauberti M, Lemarchand E, Orset C, Goulay R, Bertrand T, Emery E, Vivien D. PMID: 24846802.
GpIbα-VWF blockade restores vessel patency by dissolving platelet aggregates formed under very high shear rate in mice. Blood. 2014 May 22; 123(21):3354-63. Le Behot A, Gauberti M, Martinez De Lizarrondo S, Montagne A, Lemarchand E, Repesse Y, Guillou S, Denis CV, Maubert E, Orset C, Vivien D. PMID: 24553181.
Intracerebral hematomas disappear on T2*-weighted images during normobaric oxygen therapy. Stroke. 2013 Dec; 44(12):3482-9. Gaberel T, Gakuba C, Hebert M, Montagne A, Agin V, Rubio M, Emery E, Vivien D, Gauberti M. PMID: 24105700.
Ultra-sensitive molecular MRI of vascular cell adhesion molecule-1 reveals a dynamic inflammatory penumbra after strokes. Stroke. 2013 Jul; 44(7):1988-96. Gauberti M, Montagne A, Marcos-Contreras OA, Le Béhot A, Maubert E, Vivien D. PMID: 23743972.
Immunotherapy blocking the tissue plasminogen activator-dependent activation of N-methyl-D-aspartate glutamate receptors improves hemorrhagic stroke outcome. Neuropharmacology. 2013 Apr; 67:267-71. Gaberel T, Macrez R, Gauberti M, Montagne A, Hebert M, Petersen KU, Touze E, Agin V, Emery E, Ali C, Vivien D. PMID: 23219658.
Memantine improves safety of thrombolysis for stroke. Stroke. 2012 Oct; 43(10):2774-81. Montagne A, Hébert M, Jullienne A, Lesept F, Le Béhot A, Louessard M, Gauberti M, Orset C, Ali C, Agin V, Maubert E, Vivien D. PMID: 22879098.
Ultra-sensitive molecular MRI of cerebrovascular cell activation enables early detection of chronic central nervous system disorders. Neuroimage. 2012 Nov 01; 63(2):760-70. Montagne A, Gauberti M, Macrez R, Jullienne A, Briens A, Raynaud JS, Louin G, Buisson A, Haelewyn B, Docagne F, Defer G, Vivien D, Maubert E. PMID: 22813950.
Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity. Cell Death Differ. 2012 Dec; 19(12):1983-91. Parcq J, Bertrand T, Montagne A, Baron AF, Macrez R, Billard JM, Briens A, Hommet Y, Wu J, Yepes M, Lijnen HR, Dutar P, Anglés-Cano E, Vivien D. PMID: 22743997.
Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals. J Neurosci. 2012 Apr 11; 32(15):5186-99. Cassé F, Bardou I, Danglot L, Briens A, Montagne A, Parcq J, Alahari A, Galli T, Vivien D, Docagne F. PMID: 22496564.
Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo. Mol Neurodegener. 2011 Oct 05; 6:68. Jullienne A, Montagne A, Orset C, Lesept F, Jane DE, Monaghan DT, Maubert E, Vivien D, Ali C. PMID: 21975018.
Impact of tissue plasminogen activator on the neurovascular unit: from clinical data to experimental evidence. J Cereb Blood Flow Metab. 2011 Nov; 31(11):2119-34. Vivien D, Gauberti M, Montagne A, Defer G, Touzé E. PMID: 21878948.
Tissue plasminogen activator prevents white matter damage following stroke. J Exp Med. 2011 Jun 06; 208(6):1229-42. Correa F, Gauberti M, Parcq J, Macrez R, Hommet Y, Obiang P, Hernangómez M, Montagne A, Liot G, Guaza C, Maubert E, Ali C, Vivien D, Docagne F. PMID: 21576385.
NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity. Cell Death Differ. 2010 May; 17(5):860-71. Baron A, Montagne A, Cassé F, Launay S, Maubert E, Ali C, Vivien D. PMID: 19911010.